|
KMID : 0613820010110040335
|
|
Journal of Life Science
2001 Volume.11 No. 4 p.335 ~ p.339
|
|
|
Effect of Thesium Chinese Turczaninow Aqua-acupuncture Solution and Astragail Radix Aqua-acupuncture Solution on Promotion/ progression of Carcinogenesis
|
|
Shon Yun-Hee
Park Sin-Hwa
Ryu Jun-Seon
Cho Kyoung-Hee
Lim Jong-Kook
Nam Kyung-Soo
|
|
|
Abstract
|
|
|
|
Cancer chemoprevention refers to the use of natural or synthetic substances to prevent initiational and promotional events that occur during the process of carcinogenesis. Thesium Chinese Turczaninow aqua-acupuncture solution (TCTAS) and Astragli Radix aqua-acupuncture solution (ARAS) were tested as the cancer chemopreventive agents using biochemical markers of carcinogenesis. The effects on the inhibition of phorbol 12- myristate 13-acetate(TPA)-induced free radical formation in HL-60 cells and the inhibition of polyamine metabolism were measured. There is significant inhibition of TAP-induced free radical formation in human leukemic cells with cells with ARAS. Proliferation of Acanthamoeba castellanii was inhibited by TCTAS and ARAS. TCTAS and ARAS positive in these assays may inhibit the carcinogenesis process and is considered promising cancer-preventing agents.
|
|
|
KEYWORD
|
|
|
cancer chemoprevenion, Thesium ChineseTurczaninow, Astragail Radix, free radical, polyamine
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|